CARDIAC AUTOANTIBODIES

Cardiac Autoantibodies

1. A high proportion of rabbits immunized with pooled rabbit heart homogenates in complete Freund's adjuvant responded with the production of multiple precipitating antibodies to soluble rabbit heart antigens. The most potent antisera revealed at least five distinct antigens. 2. Rabbit anti-rabbit heart antibodies reacted with similar antigens in other mammalian hearts, (human, rat, guinea pig,...

Anti-Human Cardiac Myosin Autoantibodies

Cardiac autoantibodies in dilated cardiomyopathy become undetectable with disease progression.

OBJECTIVE To determine the relation of cardiac autoantibody and disease status in a consecutive series of patients with dilated cardiomyopathy by prospective antibody testing at diagnosis and at follow up. METHODS Antibody status was assessed by indirect immunofluorescence in 110 patients with dilated cardiomyopathy (85 male, mean (SD) age 44 (13) years) at diagnosis and at follow up (mean (S...

Sperm Autoantibodies

Clinically, antibodies against sperm are found in 3% to 12% of men who undergo evaluation for infertility and can be found in the serum, seminal plasma or sperm-bound. As antibodies in the serum cannot logistically bind to sperm unless they transudate into semen, these immunoglobulins are considered clinically less important than sperm-bound antibodies. The presence of anti-sperm antibodies in ...

Sperm Autoantibodies

Clinically, antibodies against sperm are found in 3% to 12% of men who undergo evaluation for infertility and can be found in the serum, seminal plasma or sperm-bound. As antibodies in the serum cannot logistically bind to sperm unless they transudate into semen, these immunoglobulins are considered clinically less important than sperm-bound antibodies. The presence of anti-sperm antibodies in ...